Red cell aplasia following prolonged D-penicillamine therapy.

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Red cell aplasia following prolonged D-penicillamine therapy.

Red cell aplasia developed in a case of Wilson's disease following an increase in D-penicillamine dosage after 14 years' treatment. In vitro study of the effect of D-penicillamine on 59Fe incorporation by marrow cells did not suggest that the patient's erythropoiesis was particularly sensitive to D-penicillamine or determine the mechanism of drug toxicity. However, three weeks after the drug wa...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1976

ISSN: 0021-9746

DOI: 10.1136/jcp.29.2.135